The Celsius® S3 Benchtop System is a laboratory instrument made to evaluate freeze & thaw processes of new drug candidates in single-use bags with full scalability to production-scale Celsius® platforms (FFT, FFTp and CFT).

Catalog No.: 
FTH-CS00000-0001

*Custom/bulk order quotes are provided within 72 hours of request.

The Celsius® S3 Benchtop System is the only lab-scale freeze & thaw system for single-use bags that is scalable to our production-scale Celsius® platforms (FFT, FFTp and CFT). This system is a tool to execute freeze & thaw process development and stability studies using a minimal amount of product.

Scalability

Using the same freeze & thaw critical process parameters and materials of construction as seen in all Celsius® Paks, the Celsius® S3 Benchtop System ensures unmatched scalability across systems of all scales.

Ease of Use

The CryoPilot Control Unit provides automated operation and data collection. The Celsius® S3 Benchtop System freezes and thaws 1 to 10 product samples per run. Lab-scale Celsius® Pak PDS are available in 30mL and 100mL nominal fill volumes with various filling port and thermowell configurations.

Improved Process Validation

The Celsius® S3 Benchtop System offers excellent batch-to-batch reproducibility as well as consistent product stability after freezing, thawing, and storing. The Celsius® S3 Benchtop System allows for documented and reproducible freeze & thaw processes, thus facilitating validation of your freeze & thaw operations.

Celsius® S3 Benchtop System Applications:

  • Process development studies to understand decoupling (hold) steps during downstream processing, e.g., frozen storage of process intermediates or drug substances. Explore the Celsius® technology for future scale-up. (FFT, FFTp and CFT)
  • Scale-down storage and transportation studies (using minimal volumes as low as 20mL) for understanding extended drug substance storage and shipping in terms of time and temperature
  • Formulation development of freeze & thaw compatible formulations for drug substances
  • Stability Studies in accordance with industry guidelines, conducted in freezing and thawing conditions as well as in a container closure system that is the same as or simulates the packaging proposed for freezing, storage, shipping, and thawing at production-scale

Accessories Information

  • Software
    Cryopilot® 5

Applications

  • Application Area
    • Frozen Storage & Shipping
    • Frozen Storage & Shipping
    • Frozen Storage & Shipping
    • Frozen Storage & Shipping
    • Frozen Storage & Shipping
    • Frozen Storage & Shipping
    • Frozen Storage & Shipping
    • Frozen Storage & Shipping
    • Frozen Storage & Shipping
  • Process Step
    • 8799058625120
    • 8799058723424
    • 8799058756192
    • 8799058330208

Dimensions

  • Dimensions WxDxH
    1880 x 760 x 710 mm

Features

  • Languages
    English
  • Load Capacity
    10× Lab-scale Celsius® Pak

General Specifications

  • Additional Product Specifications
    Control unit: Laptop computer
  • Temperature Range
    -60°C – +40°C

Materials of Construction

  • Materials of Construction
    • 302 / 304 Edelstahl-Gehäuse, klar
    • carcasa de acero inoxidable 302 / 304, claro
    • 302/304 Stainless Steel, 6061-T6 aluminum, 5052 aluminum, transparent PVC cover
    • Cuscinetto 302 / 304 in acciaio inox, trasparente
    • 302 / 304ステンレスシェル、透明
    • Escudo em aço inoxidável 302 / 304, claro
    • 302 / 304, оболочка из нержавеющей стали, чистая
    • 302 / 304 不锈钢壳,清澈
    • 302/304 Stainless Steel
    • 6061-T6 aluminum
    • 5052 aluminum
    • transparent PVC cover

Power Requirements

  • Power Plug
    8799067964000
  • Power Requirements
    230 V, 60 Hz, 20 A breaker minimum, 1 Phase

Product Information

  • Brand
    8798959338080
  • Freezer Technology
    8798995219040

Volume

  • Working Volume
    20 mL – 1 L
  • Lab-scale Celsius® Pak 100mL (MPC/MPC)

    Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.

    These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.

    Web prices – only available through online purchase

  • Lab-scale Celsius® Pak 30mL (LL/LL)

    Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.

    These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.

    Web prices – only available through online purchase

  • Lab-scale Celsius® Pak 30mL (MPC/MPC)

    Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.

    These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.

    Web prices – only available through online purchase

  • Lab-scale Celsius® Pak 30mL (LL/LL/EVA)

    Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.

    These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.

    Web prices – only available through online purchase

  • Lab-scale Celsius® Pak 30mL (LL/LL)

    Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.

    These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.

    Web prices – only available through online purchase

  • Lab-scale Celsius® Pak 100mL (LL/LL)

    Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.

    These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.

    Web prices – only available through online purchase

  • Lab-scale Celsius® Pak 100mL (LL/LL)

    Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.

    These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.

    Web prices – only available through online purchase

  • Lab-scale Celsius® Pak 30mL (MPC/MPC)

    Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.

    These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.

    Web prices – only available through online purchase

  • Lab-scale Celsius® Pak 100mL (LL/LL)

    Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.

    These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.

    Web prices – only available through online purchase

  • 100 mL Lab-scale Celsius® Pak (MPC/MPC/EVA/SIL)

    Celsius® Lab-scale implements small-scale single-use Celsius® solutions to support production-scale freezing and thawing operations with the Celsius® technology.

    Scalability is a feature unique to Celsius® . Lab-scale Celsius® Paks together with the process development tool called Celsius® S3 Benchtop System allow you to characterize the freeze & thaw processes on your biopharmaceutical product in the lab before scaling-up to the production system.